邹华;刘华荣;梅平;

• 1:长江大学化学与环境工程学院

摘要(Abstract)：

以柠檬酸为原料制备了碳点,并运用紫外-可见分光光度计、荧光分光光度计和透射电镜(TEM)对该碳点进行光谱与形貌表征。采用荧光光谱、圆二色谱以及紫外-可见吸收光谱等方法,在近生理条件下研究了碳点与人血清白蛋白(HSA)的相互作用。荧光猝灭和紫外-可见吸收光谱试验结果表明,人血清白蛋白(HSA)和碳点形成了静态复合物,相互作用力以氢键和范德华力为主,而且碳点会引起人血清白蛋白(HSA)构象发生变化。研究结果可以为碳点的生物安全性研究提供一定的理论信息。

关键词(KeyWords)： 碳点;柠檬酸;人血清白蛋白(HSA);荧光光谱;圆二色谱;紫外-可见吸收光谱

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金青年基金(21403017)

作者(Authors): 邹华;刘华荣;梅平;

DOI: 10.16088/j.issn.1001-6600.2017.02.015

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